tech1
$0.00
  • »
  • »
  • SeTau dyes near ideal in vivo 2P imaging characteristics reported by group at Harvard Medical School

SeTau dyes near ideal in vivo 2P imaging characteristics reported by group at Harvard Medical School

Recently the group of Prof. Weissleder at the Harvard Medical School has reported on two-photon beta cell specific in vivo imaging probes based on GLP1R targeting peptides labelled with a SETA 2-photon squaraine rotaxane: "Among the three compounds of potential interest, we found quite unexpectedly that a squaraine-rotaxane conjugate (2PEx-647, SeTau-647, K9-4148) had near ideal in vivo imaging characteristics". 

Susan M. Clardy et al. "Two-photon imaging of pancreatic beta cells in real time in vivo". Technology 04, 130 (2016).

Excitation Light Sources Characteristics
Product Number
(Specs Sheet)
Product Name
(Product Info)
Target Group 380 405 436 488 532 594 635 650 680 700 750 780 Medium λ abs
[nm]
ε
[M –1
cm–1]
λ em
[nm]
QY
[%]
FLT
[ns]
Buy
                   
K9-4119
K9-4119 new
SeTau-665-NHS
SeTau-665-NHS
NH2 PB 7.4 664 160000 712 53 3.1
K9-4148
K9-4148
SeTau-647-Maleimide
SeTau-647-Maleimide
SH PB 7.4 648 200000 692 45 3.2
K9-4149
K9-4149
SeTau-647-NHS
SeTau-647-NHS
NH2 PB 7.4 649 200000 695 61 3.2
K9-4169
K9-4169 new
SeTau-670-NHS
SeTau-670-NHS
NH2 PB 7.4 673 275000 694 36 1.6

Please provide following information to download software:

Your Name*:
Email ID*:
Contact Number:
Cancel