Links to Selected Products
Highly fluorescent rotaxane probes with extremely high chemical and photochemical stability, well suited for imaging applications. They also exhibit very high 2-photon action cross sections in the order of several thousand GM.
Seta-375-NHS is an extremely bright, positively charged, water-soluble amine-reactive label for excitation with the 375 – 380-nm diode laser. It combines high brightness, a large Stokes’shift of over 100 nm and a fluorescence lifetime of 4 ns when labeled to proteins.
Seta-PerCP-680, an extremely bright and photostable tandem conjugate of PerCP and a red-emitting squaraine-rotaxane is now available from SETA BioMedicals.
Seta-R-PE-670, an extremely bright and photostable tandem conjugate between R-PE and a red-emitting Seta dye is now available from SETA BioMedicals.
SETA BioMedicals produces, commercializes and licenses proprietary fluorescent tools (fluorescent dyes, probes, labels, tandems, and standards) for biomedical applications. They can be ordered over the phone (217) 417 2160, via e-mail firstname.lastname@example.org or with our on-line shopping cart and are delivered the next day in the continental USA and within days at any other destination around the world.
APC, PE and PerCP-tandem conjugates with Seta dyes for flow cytometry and immunofluorescence applications.
|Flow cytometry measurment of blood cells
stained with CD38–Seta-APC-780
Novel extremely bright and stable probes and labels based on squaraine rotaxanes
Next generation labels for proteins, oligonucleotides and other biomolecules with exceptional brightness and photostability.
Azides and proprietary DBCO derivatives for Cu-catalyzed and Cu-free click chemistry reactions
The brightest fluorescent probes and labels with exceptional 2-photon absorption cross-sections up to several thousand GE based on squaraines and squaraine rotaxanes
Luminescence lifetime labels with lifetimes from 0.5 to 32 ns for lifetime and polarization applications
FRET pairs with a wide range of Förster distances from 40 - 80 Angstrom
SETA BioMedicals offers free consultation on the use of SETA products for your application. Please call us at 217 417 2160.
The next-generation squaraine rotaxane dye SeTau-647 is currently the brightest label on the market for the Kr-ion laser line
|Quantum yields of IgG-conjugates of SeTau-647, Alexa 647 and Cy5 at various dye-to-protein ratios in phosphate buffer (pH 7.4)|
Compared to conventional cyanine dyes squaraine and squaraine-rotaxanes exhibit 10 – 50-times higher 2-photon cross-sections in the order of several thousand GE.
|Z-projection of a neuron filled with a squaraine rotaxane-labeled peptide|
Seta and SeTau dyes are a class of extremely bright and phtostable dyes for fluorescence imaging and are also well suited for STED and STORM applications.
STED image of HeLa-M cell nuclei labeled with primary antibody mAB414 and a secondary antibody labeled with SeTau-647