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01/14/2013 – Researchers at the
University of BC Canada in collaboration with SETA BioMedicals have published a paper "Ultra-sensitive and -stable Red and Near-Infrared Squaraine Fluorophores for In Vivo Two-Photon Imaging" demonstrating the excellent properties of these dyes in 2-photon imaging applications.


01/15/2014 – Zy Dyes structurally
identical to Cy Dyes from GE Healthcare are now available at much lower prices from SETA BioMedicals.


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Urbana, IL, January 2010
SETA BioMedicals, LLC has renewed the exclusive license agreement with PerkinElmer Health Sciences Inc. to provide dyes for their HTS assays.
 
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t1 TECHNOLOGY HIGHLIGHTS t1
t1 APPLICATIONS t1
 
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Labeling Technologies
Next generation labels for proteins, oligonucleotides and other biomolecules with exceptional brightness and photostability
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Highly Water-Soluble Rotaxane Labels
Novel extremely bright and stable probes and labels based on squaraine rotaxanes

Click Chemistry Reagents
Azides and proprietary DBCO derivatives for Cu-catalyzed and Cu-free click chemistry reactions

Fluorescent Dyes for 2-Photon Microscopy
The brightest fluorescent probes and labels with exceptional 2-photon absorption cross-sections up to several thousand GE based on squaraines and squaraine rotaxanes

Lifetime Labels
Lifetime labels with lifetimes from 0.5 to 32 ns for lifetime and polarization applications

FRET Labels
FRET pairs with a wide range of Förster distances from 40 - 80 Angstrom

DIGE Dyes
Fluorescent labels for two-dimensional difference gel electrophoresis (DIGE) applications suitable for all readers using Cy2, Cy3 and Cy5 filter sets - best performance, low price!

Phycobiliprotein Tandem Conjugates
PE, APC and PerCP tandems with various Fluors. Please contact us for more information or a quotation 

 

 
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Free Consultation
SETA BioMedicals offers free consultation on the use of SETA products for your application. Please call us at 217 417 2160.

 
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Immunofluorescence
The next-generation squaraine rotaxane dye SeTau 647 (K9-4149) is currently the brightest label on the market for the Kr-ion laser line

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Quantum yields of IgG-conjugates of SeTau 647, Alexa 647 and Cy5 at various dye-to-protein ratios in phosphat buffer (pH 7.4)
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Seta dyes show much higher signal enhancement (SE) on silver surfaces (SIFs): SE > 15 compared to Cy5, Alexa 647 or phycobillproteins (PE, APC) - SE ~ 6 - 7.
 
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The squaraine rotaxane SeTau 665 (K9-4113) shows record signal-enhancement on SIFs:SE ~ 75 for bulk measurements and SE ~ 400 for single-molecule measurements

2-Photon FRET
2-Photon FRET pairs and SETA FRET software for
2-photon FRET microscopy applications

 
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