Links to Selected Products
Recently the group of Prof. Weissleder at the Harvard Medical School has reported on the first generation two-photon beta cell specific in vivo imaging probes based on GLP1R targeting peptides labeled with SeTau 647 (K9-4148)
A 2-photon dye with extremely high 2PACS of up to 8500 GM and emission in the NIR is now available from SETA BioMedicals
SeTau 647-NHS (K9-4149) labelled to myelin oligodendrocyte glycoprotein (MOG) specific autoantibodies was used in study of autoantibody-boosted T-cell reactivation
Our new fluorescent molecular rotors have high sensitivity as well as a large dynamic range in both the lifetime and intensity modes.
APC, PE and PerCP-tandem conjugates with Seta dyes for flow cytometry and immunofluorescence applications.
|Flow cytometry measurment of blood cells
stained with CD38–Seta-APC-780
Novel extremely bright and stable probes and labels based on squaraine rotaxanes
Next generation labels for proteins, oligonucleotides and other biomolecules with exceptional brightness and photostability.
Proprietary clickable lifetime and 2P dyes (azides and DBCO derivatives) for Cu-catalyzed and Cu-free click chemistry reactions
Squaraine and squaraine rotaxanes based labels with exceptional 2-photon absorption cross-sections up to 10,000GE
Luminescence lifetime labels with lifetimes from 0.5 to 32 ns for lifetime and polarization applications
Large Stokes' shift fluorescent molecular rotors with high sensitivity and a large dynamic range in lifetime and intensity mode
SETA BioMedicals offers free consultation on the use of SETA products for your application. Please call us at 217 417 2160.
The next-generation squaraine rotaxane dye SeTau-647 is currently the brightest label on the market for the Kr-ion laser line
|Quantum yields of IgG-conjugates of SeTau-647, Alexa 647 and Cy5 at various dye-to-protein ratios in phosphate buffer (pH 7.4)|
Compared to conventional cyanine dyes squaraine and squaraine-rotaxanes exhibit 10 – 50-times higher 2-photon cross-sections in the order of several thousand GE.
|Z-projection of a neuron filled with a squaraine rotaxane-labeled peptide|
Seta and SeTau dyes are a class of extremely bright and phtostable dyes for fluorescence imaging and are also well suited for STED and STORM applications.
STED image of HeLa-M cell nuclei labeled with primary antibody mAB414 and a secondary antibody labeled with SeTau-647